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The Degradation Pathway of COP9 Signalosome–Cullin-RING Ubiquitin Ligase Complexes via Autophagy

In Mammalia, the COP9 signalosome (CSN) is associated with cullin-RING ubiquitin ligases (CRLs). This study focuses on the variants CSNCSN7A and CSNCSN7B, which form complexes with CRL3 and CRL4A, respectively. Although some research has been conducted on the assembly of the complexes, little is kno...

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Bibliografske podrobnosti
Principais autores: Dawadschargal Dubiel, Roland Hartig, Wolfgang Dubiel
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2026-02-01
Serija:Biomolecules
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Online dostop:https://www.mdpi.com/2218-273X/16/2/218
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