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A systematic review of treatment strategies to combat acute and chronic rejection episodes in vascularized composite allotransplantation

BackgroundVascularized composite allotransplantation (VCA) offers unique reconstructive solutions for severe tissue loss, restoring form and function. Acute and chronic rejection remains a significant barrier, with acute episodes occurring in most recipients and chronic rejection persisting as the l...

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Hauptverfasser: Leonard Knoedler, Tobias Niederegger, Thomas Schaschinger, Gabriel Hundeshagen, Robert Munzinger, Max Heiland, Curtis L. Cetrulo, Alexandre G. Lellouch
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2026-02-01
Schriftenreihe:Frontiers in Immunology
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Online-Zugang:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1733221/full
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