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A systematic review of treatment strategies to combat acute and chronic rejection episodes in vascularized composite allotransplantation

BackgroundVascularized composite allotransplantation (VCA) offers unique reconstructive solutions for severe tissue loss, restoring form and function. Acute and chronic rejection remains a significant barrier, with acute episodes occurring in most recipients and chronic rejection persisting as the l...

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Principais autores: Leonard Knoedler, Tobias Niederegger, Thomas Schaschinger, Gabriel Hundeshagen, Robert Munzinger, Max Heiland, Curtis L. Cetrulo, Alexandre G. Lellouch
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2026-02-01
coleção:Frontiers in Immunology
Assuntos:
allotransplant
rejection
rejection treatment
vascularized composite allotransplantation
VCA
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1733221/full
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