Neurodegenerative diseases: a hotbed for splicing defects and the potential therapies

Abstract Precursor messenger RNA (pre-mRNA) splicing is a fundamental step in eukaryotic gene expression that systematically removes non-coding regions (introns) and ligates coding regions (exons) into a continuous message (mature mRNA). This process is highly regulated and can be highly flexible th...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Dunhui Li, Craig Stewart McIntosh, Frank Louis Mastaglia, Steve Donald Wilton, May Thandar Aung-Htut
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2021-05-01
Цуврал:	Translational Neurodegeneration
Нөхцлүүд:	Neurodegenerative diseases Parkinson’s disease Alzheimer’s disease Alternative splicing Splicing defects Antisense oligonucleotides
Онлайн хандалт:	https://doi.org/10.1186/s40035-021-00240-7
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!