Porcine sialoadhesin (CD169/Siglec-1) is an endocytic receptor that allows targeted delivery of toxins and antigens to macrophages.

Sialoadhesin is exclusively expressed on specific subpopulations of macrophages. Since sialoadhesin-positive macrophages are involved in inflammatory autoimmune diseases, such as multiple sclerosis, and potentially in the generation of immune responses, targeted delivery of drugs, toxins or antigens...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Peter L Delputte, Hanne Van Gorp, Herman W Favoreel, Inge Hoebeke, Iris Delrue, Hannah Dewerchin, Frank Verdonck, Bruno Verhasselt, Eric Cox, Hans J Nauwynck
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Public Library of Science (PLoS) 2011-01-01
Цуврал:	PLoS ONE
Онлайн хандалт:	http://europepmc.org/articles/PMC3040196?pdf=render
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