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Susceptible cell lines for the production of porcine reproductive and respiratory syndrome virus by stable transfection of sialoadhesin and CD163

<p>Abstract</p> <p>Background</p> <p>Porcine reproductive and respiratory syndrome virus (PRRSV) causes major economic losses in the pig industry worldwide. <it>In vivo</it>, the virus infects a subpopulation of tissue macrophages. <it>In vitro</it>, PRRSV only replicates in primary pig macrophages...

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Autores principales: Delrue Iris, Van Gorp Hanne, Van Doorsselaere Jan, Delputte Peter L, Nauwynck Hans J
Formato: Artigo
Lenguaje:Inglês
Publicado: BMC 2010-06-01
Colección:BMC Biotechnology
Acceso en línea:http://www.biomedcentral.com/1472-6750/10/48
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