LARP3, LARP7, and MePCE are involved in the early stage of human telomerase RNA biogenesis
Abstract Human telomerase assembly is a highly dynamic process. Using biochemical approaches, we find that LARP3 and LARP7/MePCE are involved in the early stage of human telomerase RNA (hTR) and that their binding to RNA is destabilized when the mature form is produced. LARP3 plays a negative role i...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Portfolio
2024-07-01
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| Colección: | Nature Communications |
| Acceso en línea: | https://doi.org/10.1038/s41467-024-50422-w |
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