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A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor

<p>Abstract</p> <p>Background</p> <p>Interleukin 4 (IL-4) is a key regulator of the immune system and an important factor in the development of allergic hypersensitivity. Together with interleukin 13 (IL-13), IL-4 plays an important role in exacerbating allergic and asthmatic symptoms. For signal tr...

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書誌詳細
主要な著者: Sebald Walter, Nickel Joachim, Harrer Henning, Patiño Edwin, Klein Markus, Kraich Michael, Mueller Thomas D
フォーマット: Artigo
言語:Inglês
出版事項: BMC 2006-04-01
シリーズ:BMC Biology
オンライン・アクセス:http://www.biomedcentral.com/1741-7007/4/13
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