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A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor

<p>Abstract</p> <p>Background</p> <p>Interleukin 4 (IL-4) is a key regulator of the immune system and an important factor in the development of allergic hypersensitivity. Together with interleukin 13 (IL-13), IL-4 plays an important role in exacerbating allergic and asthmatic symptoms. For signal tr...

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Autori principali: Sebald Walter, Nickel Joachim, Harrer Henning, Patiño Edwin, Klein Markus, Kraich Michael, Mueller Thomas D
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2006-04-01
Serie:BMC Biology
Accesso online:http://www.biomedcentral.com/1741-7007/4/13
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