CiFi: accurate long-read chromosome conformation capture with low-input requirements

Abstract Hi-C characterizes three-dimensional chromatin organization, facilitates haplotype phasing, and enables genome-assembly scaffolding, but encounters difficulties across complex regions. By coupling chromosome conformation capture (3C) with PacBio HiFi long-read sequencing, here we develop a...

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Principais autores:	Sean P. McGinty, Gulhan Kaya, Sheina B. Sim, Alex Makunin, Renée L. Corpuz, Michael A. Quail, Mohamed Abuelanin, Mara K. N. Lawniczak, Scott M. Geib, Jonas Korlach, Megan Y. Dennis
格式:	Artigo
語言:	Inglês
出版:	Nature Portfolio 2025-12-01
叢編:	Nature Communications
在線閱讀:	https://doi.org/10.1038/s41467-025-66918-y
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