Divergent Evolution of <italic toggle="yes">Legionella</italic> RCC1 Repeat Effectors Defines the Range of Ran GTPase Cycle Targets

ABSTRACT Legionella pneumophila governs its interactions with host cells by secreting >300 different “effector” proteins. Some of these effectors contain eukaryotic domains such as the RCC1 (regulator of chromosome condensation 1) repeats promoting the activation of the small GTPase Ran. In this rep...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	A. Leoni Swart, Bernhard Steiner, Laura Gomez-Valero, Sabina Schütz, Mandy Hannemann, Petra Janning, Michael Irminger, Eva Rothmeier, Carmen Buchrieser, Aymelt Itzen, Vikram Govind Panse, Hubert Hilbi
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology 2020-04-01
Schriftenreihe:	mBio
Schlagworte:	amoeba bacterial evolution Acanthamoeba Dictyostelium effector protein guanine nucleotide exchange factor
Online-Zugang:	https://journals.asm.org/doi/10.1128/mBio.00405-20
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!