Legionella pneumophila exploits PI(4)P to anchor secreted effector proteins to the replicative vacuole.

The causative agent of Legionnaires' disease, Legionella pneumophila, employs the intracellular multiplication (Icm)/defective organelle trafficking (Dot) type IV secretion system (T4SS) to upregulate phagocytosis and to establish a replicative vacuole in amoebae and macrophages. Legionella-containi...

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Autores principales:	Stefan S Weber, Curdin Ragaz, Katrin Reus, Yves Nyfeler, Hubert Hilbi
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Public Library of Science (PLoS) 2006-05-01
Colección:	PLoS Pathogens
Acceso en línea:	http://europepmc.org/articles/PMC1463015?pdf=render
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