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Reprogramming of bacterial virulence by lysine acetylation

Abstract Gram-negative bacteria use a plethora of virulence factors to infect eukaryotic cells. CE-clan protease-related virulence factors were reported to act as deubiquitinases/ubiquitin-like specific proteases. Some have an additional acetyl-transferase activity. The molecular mechanisms underlyi...

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Hoofdauteurs: Ole Schmöker, Britta Girbardt, Sabrina Schulze, Gottfried J. Palm, Leona Berndt, Jens Hoppen, Nilüfer Kara, Xenia Schöps, Ruba Al-Abdulla, Klara Garz, Heike Junker, Sophie Wolfgramm, Leif Steil, Christian Hentschker, Katrin Schoknecht, Lea-Maria Mayer, Leonie Speth, Vanessa Lachmayer, Mark Dörr, Stefan Kemnitz, Stefan Müller, Jan-Wilm Lackmann, Marcus Krüger, Kay Hofmann, Uwe T. Bornscheuer, Uwe Völker, Elke Krüger, Vera Kozjak-Pavlovic, Michael Lammers
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Portfolio 2026-04-01
Reeks:Nature Communications
Online toegang:https://doi.org/10.1038/s41467-026-72244-8
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