Structural Basis for (2<i>R</i>,3<i>R</i>)-Taxifolin Binding and Reaction Products to the Bacterial Chalcone Isomerase of <i>Eubacterium ramulus</i>

The bacterial chalcone isomerase (CHI) from <i>Eubacterium ramulus</i> catalyses the first step in a flavanone-degradation pathway by a reverse Michael addition. The overall fold and the constitution of the active site of the enzyme completely differ from the well-characterised chalcone isomerase of...

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Bibliografski detalji

Glavni autori:	Gottfried J. Palm, Maren Thomsen, Leona Berndt, Winfried Hinrichs
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2022-11-01
Serija:	Molecules
Teme:	flavonoid crystal structure substrate recognition Michael addition chalcone taxifolin
Online pristup:	https://www.mdpi.com/1420-3049/27/22/7909
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