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GATA6 is predicted to regulate DNA methylation in an in vitro model of human hepatocyte differentiation

An integrated analysis of human induced pluripotent stem cells differentiating into hepatocyte-like cells unveils changes in DNA methylation and relevant transcription factors (like GATA6) that may influence hepatic development.

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Bibliografische Detailangaben
Hauptverfasser: Takahiro Suzuki, Erina Furuhata, Shiori Maeda, Mami Kishima, Yurina Miyajima, Yuki Tanaka, Joanne Lim, Hajime Nishimura, Yuri Nakanishi, Aiko Shojima, Harukazu Suzuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2022-05-01
Schriftenreihe:Communications Biology
Online-Zugang:https://doi.org/10.1038/s42003-022-03365-1
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