Tuberous sclerosis complex 2 association with RelA/p65 is critical for NF-κB activation and endothelial cell inflammation

Abstract Background Endothelial cell (EC) inflammation is a key component of many inflammatory conditions including sepsis and acute lung injury (ALI). However, the role of Tuberous Sclerosis Complex 2 (TSC2) in activating NF-κB and inflammatory response in EC has not been addressed. Methods Human p...

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Autors principals:	Imran Tahir, Rauf A. Najar, Arshad Rahman
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2026-05-01
Col·lecció:	Cell Communication and Signaling
Matèries:	TSC2 RelA/p65 ICAM-1 VCAM-1 Inflammation Endothelial cells
Accés en línia:	https://doi.org/10.1186/s12964-026-02922-z
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