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Generation and characterization of iPS cell line (SYSUSHi002-A) from PBMCs of an AML patient with TP53 mutation

We have generated an iPSCs line (IPS-AML2-C3, SYSUSHi002-A) from AML cells of a 71-year-old male Acute Myeloid Leukaemia patient with TP53 gene mutation (TP53: c.824G > A, p.Cys275Tyr) using episomal plasmids encoding the factors OCT4, SOX2, KLF4, L-MYC and human miR-302. The IPS-AML2-C3 (SYSUSHi002...

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Bibliografiske detaljer
Principais autores: Lihua Yuan, Yaqun Wang, Rongli Xie, Dongjun Lin, Xiaobo Wang
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2023-12-01
Serier:Stem Cell Research
Online adgang:http://www.sciencedirect.com/science/article/pii/S1873506123002167
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