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MDM4 enables efficient human iPS cell generation from PBMCs using synthetic RNAs

Abstract If iPS cells can be established easily and efficiently using freshly collected blood cells, it will enhance regenerative and personalized medicine. While reports of iPS derivation from blood-derived endothelial progenitor cells using RNA have been documented, none have been reported from pe...

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Autori principali: Masato Nakagawa, Mizuho Nogi, Hatsuki Doi, Ryuhei Hayashi, Tomohiko Katayama, Hirohisa Ohno, Megumi Mochizuki, Karin Hayashi, Hirohide Saito
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2025-09-01
Serie:Scientific Reports
Accesso online:https://doi.org/10.1038/s41598-025-16446-y
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