Targeting Epigenetic Modifiers Can Reduce the Clonogenic Capacities of Sézary Cells

Sézary syndrome (SS) is an aggressive leukemic variant of cutaneous T-cell lymphomas (CTCL) in which the human Telomerase Reverse Transcriptase (hTERT) gene is re-expressed. Current available treatments do not provide long-term response. We previously reported that Histone deacetylase inhibitors (HD...

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Egile Nagusiak:	Alain Chebly, Martina Prochazkova-Carlotti, Yamina Idrissi, Laurence Bresson-Bepoldin, Sandrine Poglio, Chantal Farra, Marie Beylot-Barry, Jean-Philippe Merlio, Roland Tomb, Edith Chevret
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Frontiers Media S.A. 2021-10-01
Saila:	Frontiers in Oncology
Gaiak:	cutaneous T-cell lymphomas (CTCL) Sezary syndrome (SS) 5-azacytidine romidepsin vorinostat Histone deacetylase inhibitor
Sarrera elektronikoa:	https://www.frontiersin.org/articles/10.3389/fonc.2021.775253/full
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