Improving diagnostic accuracy in atypical melanocytic tumors using p16 immunohistochemistry and 9p21 fluorescence in situ hybridization: analysis of 206 second opinion cases

Abstract Diagnosing atypical melanocytic tumors can be challenging without molecular characterization, necessitating simple tools to enhance diagnostic accuracy in daily practice. This study retrospectively analyzed the utility of p16 immunohistochemistry (IHC) and 9p21 fluorescence in situ hybridiz...

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Detalhes bibliográficos

Principais autores:	Rémi Vergara, Elodie Laharanne, Arnaud de la Fouchardière, Audrey Gros, Jean-Philippe Merlio, Mathilde Guyon, Caroline Dutriaux, Marie Beylot-Barry, Béatrice Vergier, Fanny Beltzung
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-04-01
coleção:	Scientific Reports
Assuntos:	p16 FISH Ambiguous melanocytic tumour Melanoma Naevus Second opinion
Acesso em linha:	https://doi.org/10.1038/s41598-025-95785-2
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