IL-13 induces loss of CFTR in ionocytes and reduces airway epithelial fluid absorption
The airway surface liquid (ASL) plays a crucial role in lung defense mechanisms, and its composition and volume are regulated by the airway epithelium. The cystic fibrosis transmembrane conductance regulator (CFTR) is abundantly expressed in a rare airway epithelial cell type called an ionocyte. Rec...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2024-11-01
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| Serie: | The Journal of Clinical Investigation |
| Soggetti: | |
| Accesso online: | https://doi.org/10.1172/JCI181995 |
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