Epithelial responses to CFTR modulators are improved by inflammatory cytokines and impaired by antiinflammatory drugs
Cystic fibrosis (CF) is a genetic disorder that disrupts CF transmembrane conductance regulator (CFTR) anion channels and impairs airway host defenses. Airway inflammation is ubiquitous in CF, and suppressing it has generally been considered to improve outcomes. However, the role of inflammation in...
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| Principais autores: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical investigation
2024-07-01
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| Serier: | JCI Insight |
| Fag: | |
| Online adgang: | https://doi.org/10.1172/jci.insight.181836 |
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