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Role of ATP citrate lyase and its complementary partner on fatty acid synthesis in gastric cancer

Abstract ATP citrate lyase (ACLY) and acyl-CoA short-chain synthetases 2 (ACSS2) are key enzymes in lipid metabolism. We explored the role of ACLY in gastric cancer (GC) and the effect of ACLY and ACSS2 compensation on GC growth. We used immunohistochemistry to verify the expression level of ACLY in...

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Auteurs principaux: Chunlei Li, Wenxuan Liu, Youzhao Liu, Weixing Wang, Wenhong Deng
Format: Artigo
Langue:Inglês
Publié: Nature Portfolio 2024-12-01
Collection:Scientific Reports
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Accès en ligne:https://doi.org/10.1038/s41598-024-81448-1
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