A novel direct homogeneous assay for ATP citrate lyase[S]
ATP citrate lyase (ACL) is a cytosolic enzyme that catalyzes the synthesis of acetyl-CoA and oxaloacetate using citrate, CoA, and ATP as substrates and Mg2+ as a necessary cofactor. The ACL-dependent synthesis of acetyl-CoA is thought to be an essential step for the de novo synthesis of fatty acids...
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| Principais autores: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier
2009-10-01
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| Serier: | Journal of Lipid Research |
| Fag: | |
| Online adgang: | http://www.sciencedirect.com/science/article/pii/S0022227520307227 |
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