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A novel direct homogeneous assay for ATP citrate lyase[S]

ATP citrate lyase (ACL) is a cytosolic enzyme that catalyzes the synthesis of acetyl-CoA and oxaloacetate using citrate, CoA, and ATP as substrates and Mg2+ as a necessary cofactor. The ACL-dependent synthesis of acetyl-CoA is thought to be an essential step for the de novo synthesis of fatty acids...

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Bibliografiske detaljer
Principais autores: Zhengping Ma, Ching-Hsuen Chu, Dong Cheng
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2009-10-01
Serier:Journal of Lipid Research
Fag:
Online adgang:http://www.sciencedirect.com/science/article/pii/S0022227520307227
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