Differential significance of molecular subtypes which were classified into EGFR exon 19 deletion on the first line afatinib monotherapy

Abstract Background Epidermal growth factor receptor (EGFR)-sensitizing mutation, exon 19 deletion consists of several molecular variants. Influences of these variants on clinical response to EGFR tyrosine kinase inhibitors remain elusive. Methods West Japan Oncology Group 8114LTR is a prospective,...

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Detalhes bibliográficos

Principais autores:	Nahomi Tokudome, Yasuhiro Koh, Hiroaki Akamatsu, Daichi Fujimoto, Isamu Okamoto, Kazuhiko Nakagawa, Toyoaki Hida, Fumio Imamura, Satoshi Morita, Nobuyuki Yamamoto
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2020-02-01
coleção:	BMC Cancer
Assuntos:	NSCLC Afatinib EGFR mutation Exon 19 deletion Molecular subtypes
Acesso em linha:	https://doi.org/10.1186/s12885-020-6593-1
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