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Afatinib After Progression on Osimertinib in EGFR-Mutated Non-Small Cell Lung Cancer

ABSTRACT: Introduction: After the development of acquired resistance to osimertinib, the standard-of-care treatment for advanced EGFR-mutated NSCLC is chemotherapy. Whether afatinib, a pan-ErbB family tyrosine kinase inhibitor, is active after progression on osimertinib is unknown. Methods: We cond...

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Auteurs principaux: Jacqueline V Aredo, Heather A Wakelee, Joel W Neal, Sukhmani K Padda
Format: Artigo
Langue:Inglês
Publié: Elsevier 2022-01-01
Collection:Cancer Treatment and Research Communications
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Accès en ligne:http://www.sciencedirect.com/science/article/pii/S2468294221001933
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