Cardiac Fibroblast-Specific Knockout of PGC-1α Accelerates AngII-Induced Cardiac Remodeling

Cardiac remodeling consisted of ventricular hypertrophy and interstitial fibrosis is the pathological process of many heart diseases. Fibroblasts as one of the major cells in the myocardium regulate the balance of the generation and degeneration of collagen, and these cells transform toward myofibro...

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Principais autores:	Hong-jin Chen, Xiao-xi Pan, Li-li-qiang Ding, Cheng-chao Ruan, Ping-jin Gao
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2021-06-01
coleção:	Frontiers in Cardiovascular Medicine
Assuntos:	cardiac fibroblast fibrosis PGC-1α cardiac remodeling AngII
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fcvm.2021.664626/full
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