Induction of Proteasome Subunit Low Molecular Weight Protein (LMP)-2 Is Required to Induce Active Remodeling in Adult Rat Ventricular Cardiomyocytes

Isolated adult rat ventricular cardiomyocytes (ARVC) adapt to the two-dimensional surface of culture dishes once they are isolated from the three-dimensional heart tissue. This process mimics aspects of cardiac adaptation to pressure overload and requires an initial breakdown of sarcomeric structure...

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Autores principales:	Antonia Petersen, Hanna Sarah Kutsche, Franziska Nippert, Rolf Schreckenberg, Rainer Schulz, Klaus-Dieter Schlüter
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2020-05-01
Colección:	Medical Sciences
Materias:	cardiac remodeling cardiac hypertrophy proteasome
Acceso en línea:	https://www.mdpi.com/2076-3271/8/2/21
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