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Dichotomic response to interleukin-6 blockade in idiopathic multicentric Castleman disease: two case reports

Abstract Background Human herpervirus-8/human immunodeficiency virus negative Idiopathic multicentric Castleman disease (iMCD) is a lymphoproliferative disorder sustained by a pro-inflammatory condition of hypercytokinemia mostly mediated by Interleukin-6 (IL-6). According to iMCD consensus guidelin...

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Principais autores: Simone Ferrero, Simone Ragaini
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2021-03-01
Serier:Journal of Medical Case Reports
Fag:
Idiopathic
Multicentric
Castleman
iMCD
IL-6
Blockade
Online adgang:https://doi.org/10.1186/s13256-021-02726-4
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