NHR-8 and P-glycoproteins uncouple xenobiotic resistance from longevity in chemosensory C. elegans mutants

Longevity is often associated with stress resistance, but whether they are causally linked is incompletely understood. Here we investigate chemosensory-defective Caenorhabditis elegans mutants that are long-lived and stress resistant. We find that mutants in the intraflagellar transport protein gene...

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Principais autores:	Gabriel A Guerrero, Maxime J Derisbourg, Felix AMC Mayr, Laura E Wester, Marco Giorda, J Eike Dinort, Matías D Hartman, Klara Schilling, María José Alonso-De Gennaro, Ryan J Lu, Bérénice A Benayoun, Martin S Denzel
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	eLife Sciences Publications Ltd 2021-08-01
סדרה:	eLife
נושאים:	longevity aging chemosensory mutants xenobiotic detoxification
גישה מקוונת:	https://elifesciences.org/articles/53174
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!