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NHR-8 and P-glycoproteins uncouple xenobiotic resistance from longevity in chemosensory C. elegans mutants

Longevity is often associated with stress resistance, but whether they are causally linked is incompletely understood. Here we investigate chemosensory-defective Caenorhabditis elegans mutants that are long-lived and stress resistant. We find that mutants in the intraflagellar transport protein gene...

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Bibliografiset tiedot
Päätekijät: Gabriel A Guerrero, Maxime J Derisbourg, Felix AMC Mayr, Laura E Wester, Marco Giorda, J Eike Dinort, Matías D Hartman, Klara Schilling, María José Alonso-De Gennaro, Ryan J Lu, Bérénice A Benayoun, Martin S Denzel
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: eLife Sciences Publications Ltd 2021-08-01
Sarja:eLife
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Linkit:https://elifesciences.org/articles/53174
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