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Genome mining reveals the unique function of UbiA-type prenyltransferase in Laetiporus sulphureus

Abstract Eight UbiA-type prenyltransferases were mined in Laetiporus sulphureus by bioinformatic analysis, and phylogenetic analysis showed that they have unique functions. Through heterologous expression in Aspergillus oryzae and addition of exogenous hydroquinone (HYQ, 2) substrate, it was found t...

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Principais autores: Yue Wang, Qian Wang, Chunlei Wang, Pengchao Wang, Ran Wang, Jing Wu, Hirokazu Kawagishi, Chengwei Liu
Format: Artigo
Sprog:Inglês
Udgivet: SpringerOpen 2026-01-01
Serier:Natural Products and Bioprospecting
Fag:
Laetiporus sulphureus
UbiA prenyltransferase
Heterologous expression
Targeted mutation
Aspergillus oryzae
Online adgang:https://doi.org/10.1007/s13659-025-00571-2
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