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Innate And Adaptive Immunity are Progressively Activated in Parallel with Renal Injury in the 5/6 Renal Ablation Model

Abstract The mechanisms triggering renal inflammation in chronic kidney disease (CKD) are unclear. We performed a detailed analysis of the time course of innate and adaptive immunity activation in the 5/6 renal ablation (Nx) model. Munich-Wistar rats undergoing Nx were studied 15, 60 and 120 days af...

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Главные авторы: Camilla Fanelli, Simone C. A. Arias, Flavia G. Machado, Jessica K. Okuma, Denise M. A. C. Malheiros, Hatylas Azevedo, Carlos A. Moreira-Filho, Niels O. S. Camara, Clarice K. Fujihara, Roberto Zatz
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Portfolio 2017-06-01
Серии:Scientific Reports
Online-ссылка:https://doi.org/10.1038/s41598-017-02915-6
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