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Simplified and Rapid Determination of Primaquine and 5,6-Orthoquinone Primaquine by UHPLC-MS/MS: Its Application to a Pharmacokinetic Study

The method for the determination of primaquine (PQ) and 5,6-orthoquinone primaquine (5,6-PQ), the representative marker for PQ active metabolites, via CYP2D6 in human plasma and urine has been validated. All samples were extracted using acetonitrile for protein precipitation and analyzed using the u...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Waritda Pookmanee, Siriwan Thongthip, Jeeranut Tankanitlert, Mathirut Mungthin, Chonlaphat Sukasem, Supeecha Wittayalertpanya
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: MDPI AG 2021-07-01
Sraith:Molecules
Ábhair:
Rochtain ar líne:https://www.mdpi.com/1420-3049/26/14/4357
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