Mitochondrial contact site and cristae organizing system (MICOS) machinery supports heme biosynthesis by enabling optimal performance of ferrochelatase

Heme is an essential cofactor required for a plethora of cellular processes in eukaryotes. In metazoans the heme biosynthetic pathway is typically partitioned between the cytosol and mitochondria, with the first and final steps taking place in the mitochondrion. The pathway has been extensively stud...

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Автори:	Jonathan V. Dietz, Mathilda M. Willoughby, Robert B. Piel, III, Teresa A. Ross, Iryna Bohovych, Hannah G. Addis, Jennifer L. Fox, William N. Lanzilotta, Harry A. Dailey, James A. Wohlschlegel, Amit R. Reddi, Amy E. Medlock, Oleh Khalimonchuk
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Elsevier 2021-10-01
Серія:	Redox Biology
Предмети:	Mitochondria Heme MICOS Ferrochelatase Yeast
Онлайн доступ:	http://www.sciencedirect.com/science/article/pii/S2213231721002846
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Mitochondrial contact site and cristae organizing system (MICOS) machinery supports heme biosynthesis by enabling optimal performance of ferrochelatase

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