Coxiella burnetii effector CvpE maintains biogenesis of Coxiella-containing vacuoles by suppressing lysosome tubulation through binding PI(3)P and perturbing PIKfyve activity on lysosomes

Coxiella burnetii (C. burnetii) is the causative agent of Q fever, a zoonotic disease. Intracellular replication of C. burnetii requires the maturation of a phagolysosome-like compartment known as the replication permissive Coxiella-containing vacuole (CCV). Effector proteins secreted by the Dot/Icm...

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Autori principali:	Mingliang Zhao, Shan Zhang, Weiqiang Wan, Chunyu Zhou, Nana Li, Ruxi Cheng, Yonghui Yu, Xuan Ouyang, Dongsheng Zhou, Jun Jiao, Xiaolu Xiong
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis Group 2024-12-01
Serie:	Virulence
Soggetti:	Coxiella burnetii effector proteins Coxiella-containing vacuoles lysosomes Coxiella vacuolar protein E
Accesso online:	https://www.tandfonline.com/doi/10.1080/21505594.2024.2350893
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