Evaluation of a Boron-Conjugated SRC Inhibitor Combined with Proton and X-Ray Irradiation in U-87 MG and U-87 MG IDH1^R132H Glioma Cell Lines

<b>Background</b>: Adult diffuse gliomas represent one of the most aggressive types of brain tumors. Proton therapy offers a minimally invasive treatment option whose biological effectiveness may be enhanced through nuclear reactions involving boron atoms, leading to the emission of high-LET α-parti...

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Autors principals:	Cristiana Alberghina, Filippo Torrisi, Samuel Valable, Elsa Sarrazin, Isis Blanchard, Anthony Vela, Valentina Bravatà, Lorenzo Botta, Luca Lanzanò, Silvia Scalisi, Maria P. Demichelis, Maria G. Sabini, Iolanda V. Patti, Giorgio Russo, Francesco P. Cammarata, Rosalba Parenti
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2026-02-01
Col·lecció:	Pharmaceuticals
Matèries:	glioblastoma radiosensitivity targeted therapy DNA damage
Accés en línia:	https://www.mdpi.com/1424-8247/19/3/392
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