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CGF-Conditioned Medium Modulates Astrocytic Differentiation and Invasiveness in U87MG Glioblastoma Cells

Background: Glioblastoma (GBM) is a highly aggressive tumor characterized by elevated plasticity and poor differentiation. Platelet-derived preparations such as Concentrated Growth Factors (CGF) are rich in bioactive molecules, but their effects on tumor biology remain underexplored. Methods: U87MG...

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Principais autores: Laura Giannotti, Benedetta Di Chiara Stanca, Francesco Spedicato, Christian Demitri, Eleonora Stanca, Andrea Palermo, Franco Ferrante, Fabrizio Damiano, Maria Antonietta De Sangro, Luciano Abbruzzese, Luisa Siculella
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2025-10-01
coleção:Biology
Assuntos:
astrocyte-like phenotype
concentrated growth factors (CGF)
glioblastoma differentiation
tumor plasticity
U87MG
Acesso em linha:https://www.mdpi.com/2079-7737/14/10/1461
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