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Andrographolide binds to spike glycoprotein and RNA-dependent RNA polymerase (NSP12) of SARS-CoV-2 by in silico approach: a probable molecule in the development of anti-coronaviral drug

Abstract The SARS-CoV-2 belongs to Coronaviridae family infects host cells by the interaction of its spike glycoprotein and angiotensin-converting enzyme 2 (ACE 2) of host cells. Upon entry, the virus uses its RNA dependent RNA polymerase (NSP12) for transcribing its genome to survive in the cell an...

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Principais autores: Lokanathan Srikanth, Potukuchi Venkata Gurunadha Krishna Sarma
פורמט: Artigo
שפה:Inglês
יצא לאור: Elsevier 2021-07-01
סדרה:Journal of Genetic Engineering and Biotechnology
נושאים:
גישה מקוונת:https://doi.org/10.1186/s43141-021-00201-7
תגים: הוספת תג
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