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Computational Analysis Reveals Monomethylated Triazolopyrimidine as a Novel Inhibitor of SARS-CoV-2 RNA-Dependent RNA Polymerase (RdRp)

The human population is still facing appalling conditions due to several outbreaks of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) virus. The absence of specific drugs, appropriate vaccines for mutants, and knowledge of potential therapeutic agents makes this situation more difficult...

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Principais autores: Anandakrishnan Karthic, Veerbhan Kesarwani, Rahul Kunwar Singh, Pavan Kumar Yadav, Navaneet Chaturvedi, Pallavi Chauhan, Brijesh Singh Yadav, Sandeep Kumar Kushwaha
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-01-01
Serier:Molecules
Fag:
SARS-CoV-2
triazolopyrimidine
RNA-dependent RNA polymerase (RdRp)
essramycin
non-structural proteins (NSP)
Remdesivir
Online adgang:https://www.mdpi.com/1420-3049/27/3/801
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