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Atorvastatin Induces Mitochondria-Dependent Ferroptosis via the Modulation of Nrf2-xCT/GPx4 Axis

As one of the cornerstones of clinical cardiovascular disease treatment, statins have an extensive range of applications. However, statins commonly used have side reactions, especially muscle-related symptoms (SAMS), such as muscle weakness, pain, cramps, and severe condition of rhabdomyolysis. This...

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Váldodahkkit: Qi Zhang, Hang Qu, Yinghui Chen, Xueyang Luo, Chong Chen, Bing Xiao, Xiaowei Ding, Pengjun Zhao, Yanan Lu, Alex F. Chen, Yu Yu
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Frontiers Media S.A. 2022-03-01
Ráidu:Frontiers in Cell and Developmental Biology
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Liŋkkat:https://www.frontiersin.org/articles/10.3389/fcell.2022.806081/full
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