PSAT1 inhibits ferroptosis in osteosarcoma cells by activating the Xct/GPX4 signaling axis

Abstract Osteosarcoma is a prevalent primary malignant bone tumor predominantly affecting children and adolescents, characterized by a poor survival rate and prognosis. Currently, ferroptosis is a newly defined form of cell death, but the mechanism between it and osteosarcoma is unclear. To further...

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Detalhes bibliográficos

Principais autores:	Po Wang, Jun Xiao, Jin Zeng, Feng Yang, Mingchao Lin, Tao Liang, Hucheng Liu, Haibo Zhan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-07-01
Colecção:	Scientific Reports
Assuntos:	PSAT1 Osteosarcoma Ferroptosis Bioinformatics analysis
Acesso em linha:	https://doi.org/10.1038/s41598-025-09568-w
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