Dysregulated mitochondrial homeostasis and DNA repair in the progression from colon adenoma to cancer

Abstract Background While nuclear DNA (nDNA) damage and alterations in nDNA repair are known to play a role in colon cancer (CC), there is insufficient research investigating these processes in mitochondrial DNA (mtDNA). Methods This study investigates mtDNA changes in CC, focusing on mitochondrial...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Natalie Danesova, Josef Horak, Anna Valickova, Adrian Gil-Korilis, Jorge Ergui-Arbizu, Richard Palek, Jan Bruha, Miroslav Levy, Pavel Skrobanek, Jan Kral, Jiri Jungwirth, Jiri Neuzil, Veronika Vymetalkova, Pavel Vodicka, Sona Vodenkova, Kristyna Tomasova
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2025-11-01
Edice:	Molecular Medicine
Témata:	Colorectal cancer Colon adenomas Biomarkers Mitochondria Mitochondrial DNA damage Mitochondrial DNA repair
On-line přístup:	https://doi.org/10.1186/s10020-025-01400-5
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!