Exploring the K+ binding site and its coupling to transport in the neurotransmitter:sodium symporter LeuT

The neurotransmitter:sodium symporters (NSSs) are secondary active transporters that couple the reuptake of substrate to the symport of one or two sodium ions. One bound Na+ (Na1) contributes to the substrate binding, while the other Na+ (Na2) is thought to be involved in the conformational transiti...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Solveig G Schmidt, Andreas Nygaard, Joseph A Mindell, Claus J Loland
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	eLife Sciences Publications Ltd 2024-01-01
Schriftenreihe:	eLife
Schlagworte:	Aquifex aeolicus structure-function relationships membrane transport secondary active transport transition metal ion FRET ion binding site
Online-Zugang:	https://elifesciences.org/articles/87985
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