Exploring the K+ binding site and its coupling to transport in the neurotransmitter:sodium symporter LeuT

The neurotransmitter:sodium symporters (NSSs) are secondary active transporters that couple the reuptake of substrate to the symport of one or two sodium ions. One bound Na+ (Na1) contributes to the substrate binding, while the other Na+ (Na2) is thought to be involved in the conformational transiti...

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Главные авторы:	Solveig G Schmidt, Andreas Nygaard, Joseph A Mindell, Claus J Loland
Формат:	Artigo
Язык:	Inglês
Опубликовано:	eLife Sciences Publications Ltd 2024-01-01
Серии:	eLife
Предметы:	Aquifex aeolicus structure-function relationships membrane transport secondary active transport transition metal ion FRET ion binding site
Online-ссылка:	https://elifesciences.org/articles/87985
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