MEDAG expression in vitro and paeoniflorin alleviates bone loss by regulating the MEDAG/AMPK/PPARγ signaling pathway in vivo

Objectives: Osteoporosis (OP) is characterized by reduced bone mass and impaired bone microstructure. Paeoniflorin (PF) is isolated from peony root with anti-inflammatory, immunomodulatory, and bone-protective effects. Up to now, the mechanism of anti-OP in PF has not been completely clarified. Meth...

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Principais autores:	Haixia Liu, Zhiyue Chang, Shuling Liu, Ruyuan Zhu, Jiayi Ma, Xinyue Lu, Lei Li, Zhiguo Zhang
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2024-01-01
Series:	Heliyon
Assuntos:	Osteoporosis Paeoniflorin Ovariectomized MEDAG/AMPK/PPARγ signaling pathway Lipid metabolism
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S240584402400272X
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