Comprehensive assessments of germline deletion structural variants reveal the association between prognostic MUC4 and CEP72 deletions and immune response gene expression in colorectal cancer patients

Abstract Background Functional disruptions by large germline genomic structural variants in susceptible genes are known risks for cancer. We used deletion structural variants (DSVs) generated from germline whole-genome sequencing (WGS) and DSV immune-related association tumor microenvironment (TME)...

पूर्ण विवरण

ग्रंथसूची विवरण

मुख्य लेखकों:	Peng-Chan Lin, Hui-O Chen, Chih-Jung Lee, Yu-Min Yeh, Meng-Ru Shen, Jung-Hsien Chiang
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	BMC 2021-01-01
श्रृंखला:	Human Genomics
विषय:	Whole-genome sequencing Cancer risk Deletion structural variants MUC4 CEP72
ऑनलाइन पहुंच:	https://doi.org/10.1186/s40246-020-00302-3
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