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CCHCR1-astrin interaction promotes centriole duplication through recruitment of CEP72

Abstract Background The centrosome is one of the most important non-membranous organelles regulating microtubule organization and progression of cell mitosis. The coiled-coil alpha-helical rod protein 1 (CCHCR1, also known as HCR) gene is considered to be a psoriasis susceptibility gene, and the pro...

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Autori principali: Zhenguang Ying, Kaifang Wang, Junfeng Wu, Mingyu Wang, Jing Yang, Xia Wang, Guowei Zhou, Haibin Chen, Hongwu Xu, Stephen Cho Wing Sze, Feng Gao, Chunman Li, Ou Sha
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2022-10-01
Serie:BMC Biology
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Accesso online:https://doi.org/10.1186/s12915-022-01437-6
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