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Computational methods for ab initio detection of microRNAs

MicroRNAs are small RNA sequences of 18-24 nucleotides in length, which serve as templates to drive post transcriptional gene silencing. The canonical microRNA pathway starts with transcription from DNA and is followed by processing via the Microprocessor complex, yielding a hairpin structure. Which...

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Autors principals: Malik eYousef, Jens eAllmer
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2012-10-01
Col·lecció:Frontiers in Genetics
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Accés en línia:http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00209/full
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