Approaches to manipulating microRNAs in neurogenesis

Neurogenesis in the nervous system is regulated by both protein coding genes and noncoding RNA molecules. microRNAs (miRNAs) are endogenous small noncoding RNAs and usually negatively regulate gene expression by binding to the 3’ untranslated region (3’UTR) of target messenger RNAs (mRNAs). miRNAs...

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主要な著者:	Haijun eZhang, Benjamin eShykind, Tao eSun
フォーマット:	Artigo
言語:	Inglês
出版事項:	Frontiers Media S.A. 2013-01-01
シリーズ:	Frontiers in Neuroscience
主題:	MicroRNAs Neurogenesis loss-of-function gain-of-function miRNA inhibitor miRNA sponge
オンライン･アクセス:	http://journal.frontiersin.org/Journal/10.3389/fnins.2012.00196/full
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